Opioid Analgesic REMS for Accredited Continuing Education Providers

The Opioid Analgesic Risk Evaluation Mitigation Strategies (REMS) was designed to ensure that the benefits of opioid analgesics used in the outpatient setting outweigh the risks (in patients whose clinicians have determined opioid analgesics to be an appropriate treatment option). The FDA has required manufacturers of opioid analgesics to make education available for providers of these medications. These manufactures have developed and are implementing this REMS through a consortium known as the REMS Program Companies (RPC). RPC-supported REMS education is provided through accredited continuing education (CE) activities supported by independent educational grants from the RPC. The FDA has developed an Opioid Analgesic REMS Education Blueprint for Health Care Providers Involved in the Treatment and Monitoring of Patients with Pain ("FDA Blueprint") on which the content of these accredited CE activities is based.

To date, the RPC has completed nine CE grant cycles - see the table below for a listing of grantees. All accredited CE activities from the 2012-2021 CE Grant Cycles have been completed. As of November 2023, there is a list of 206 ongoing RPC-supported REMS-compliant accredited CE activities. Please note that certain accredited CE provider grantees are still finalizing dates/locations for some of the activities. Check back often as this listing is updated on a regular basis.

Primary Provider Title
California Academy of Family Physicians The Power of Trust: Clinician associations helping providers address the public health challenges of chronic pain and opioid use disorder
American Society of Anesthesiologists 2023 Principles for Good Perioperative Pain Management
Trustees of Boston University Safer/Competent Opioid Prescribing Education - SCOPE of Pain: Educating the Healthcare Team
Purdue University Opioid Analgesics REMS: Paving the Way for Safe and Effective Solutions
Howard University Addressing Racial Disparities in Pain Management and Opioid Analgesia: The Role of the Pharmacist in Improving Best Practice
Pri-Med Institute, LLC P.A.C.T.: Practical Approaches to Comprehensive Treatment of Pain
Massachusetts Medical Society NEJM Knowledge+ Pain Management and Opioids
Cleveland Clinic The Role of Behavioral Medicine in Reducing Opioid Use
Clinical Care Options Applying Best Practices in Pain Management: Delivering Holistic Patient-Centered Care to Minimize Health Disparities and Adverse Opioid Outcomes
CME Outfitters, LLC Finding Balance: Optimizing the Treatment of Patients
American College of Osteopathic Family Physicians Evidence-Based Strategies to Mitigate Opioid Prescribing for Pain Management: Navigating Alternatives and Emphasizing Safety
Evolve Medical Education, LLC The Basics of Pain Management for Cancer Patients: From Diagnosis to Palliative Care
Talem Health, LLC Tackling the Opioid Crisis in South Carolina: Strategies to Improve Best Practices and Patient Outcomes
Primary Provider Title
Trustees of Boston University Safer/Competent Opioid Prescribing Education - SCOPE of Pain: Educating the Healthcare Team
University of Illinois Using Academic Detailing to improve appropriate use and monitoring of opioids
American Society of Health-Systems Pharmacists Safely Managing our Patients’ Pain: An Opioid Analgesic REMS-compliant Accredited CE Initiative for Pharmacists
California Academy of Family Physicians CO*RE
Pri-Med Institute, LLC (d.b.a pmiCME) Strategies for Effective Pain Management in Clinical Practice
Massachusetts Medical Society NEJM Knowledge+ Pain Management and Opioids
Postgraduate Institute for Medicine Tackling the Opioid Crisis in Kentucky: Strategies to Improve Best Practices and Patient Outcomes
UKHC CECentral Functional Pain and Opioids Clinically Useful Strategies (FOCUS) on Pain Management
Clinical Care Options, LLC Opioid REMS Patient-Centered Pain Management: An Expert's Guide to Safe, Effective,and Appropriate Care for Patients with Pain
American Society of Hematology Effective Management of Pain Along the Treatment of Hematologic MalignancY (EMPATHY)
CME Outfitters, LLC Translating Data to Practice to Optimize the Lives of Patients with Pain
Medicus Consultants in Education, Inc Delivering Results Through Small Groups: Using Completion of a REMS-Compliant Curriculum to Effect Change in Culturally Diverse Populations
Primary Provider Title
Trustees of Boston University Safer/Competent Opioid Prescribing Education - SCOPE of Pain: Educating the Healthcare Team
Pri-Med Institute, LLC (d.b.a. pmiCME) Strategies for Effective Pain Management in Clinical Practice
Purdue University Opioid REMS: Moving Forward, Safely and Effectively
Massachusetts Medical Society NEJM Knowledge+ Pain Management and Opioids
Postgraduate Healthcare Education, LLC Opioid Education: Special Populations Based on Age, Occupation, Sex, or Behaviors
Postgraduate Institute for Medicine Tackling the Opioid Crisis in West Virginia: Strategies to Improve Best Practices and Patient Outcomes
UKHC CECentral PEDIATRIC- Pain Evaluation During Infancy thru Adolescence: Treatment Impact and Considerations
Clinical Care Options, LLC Expert Guidance for Effective Management and Appropriate Monitoring of Patients with Pain
American Society of Anesthesiologists Pain Management Considerations For the Anesthesiologist By the Anesthesiologist
Medicus Consultants in Education, Inc It Takes a Group: Opioid Analgesic REMS Initiative
CME Outfitters, LLC OA 110121: On Point with Pain Management: Leveraging Change for Positive Outcomes
Antidote Education Company FIRST DO NO HARM: STRATEGIES FOR MANAGING NON-CANCER PAIN IN YOUR CLINIC
UMA Education, Inc. dba Global Education Group MANAGING OPIOID RISK IN ACUTE AND CHRONIC PAIN
Primary Provider Title
American Society of Health System Pharmacists Protecting Our Patients: An Opioid Analgesic REMS-compliant Accredited CE Initiative for Pharmacists
Trustees of Boston University Safer/Competent Opioid Prescribing Education – SCOPE of Pain Educating the Healthcare Team
Massachusetts Medical Society NEJM Knowledge+ Pain Management and Opioids, with additional learning resources
AKH Inc., Advancing Knowledge in Healthcare Managing Opioid Risk on the Front Lines: Focus on Active Military Service Members and Veterans
USF Health Professions Conferencing Corporation Evidence-based Pain Management: Addressing the Growing Role of Nurse Practitioners and Physician Assistants in Managing Patients with Acute and Chronic Pain
Pri-Med Institute Strategies for Effective Pain Management
CME Outfitters Heeding the Call for Safe and Responsible Pain Management in Our Communities
Howard University Howard University Second Opioid Symposium and Naloxone Administration Training for Pharmacy Professionals
Horizon CME Avoiding Risks While Managing Pain: Following the REMS Blueprint for Pain Management
Medicus Consultants in Education It Takes a Group: Utilizing a Group-Based Model to Drive Completion of a REMS-Compliant Curriculum at Jefferson Health and Hackensack Meridian Health
Postgraduate Healthcare Education Building Pharmacist Skills in Opioid Analgesic Therapy: The Power-Pak C.E. Opioid Analgesic Therapy Certificate Program for Pharmacists
University of Kentucky Pain COACH: Pain Assessment Interventions Needed when Considering Older Adult Care for Healthcare providers
Primary Provider Title
Trustees of Boston University Safe and Competent Opioid Prescribing Education – SCOPE of Pain Educating the Healthcare Team
Johns Hopkins University Get SMART 'Mobile'- Safe Means of Administering the Right Therapy
MediCom Worldwide, Inc. Safe and Effective Prescribing of Opioid Analgesics: A Hands-on Case-based Clinical Curriculum
Postgraduate Institute for Medicine Get SMART – Safe Means of Administering the Right Therapy (Get SMART Nationals)
Postgraduate Institute for Medicine Talem ACO Summit Series: Safe and Appropriate Opioid Prescribing: A Systems-based Approach
American Society of Anesthesiologists ASA Pain: Anesthesiologists Tailored Approach to Patient Safety Considerations When Using Opioid Analgesics
University of North Texas Health Science Center Opioid Analgesic: Risk Evaluation and Mitigation Strategy (REMS)
Antidote Education Company First Do No Harm: Safe and Effective Management of Chronic Pain
CO*RE CO*RE's Pain Management and Opioids: Balancing Risks and Benefits
University of Kentucky Get SMART – Safe Means of Administering the Right Therapy – University of Kentucky
Howard University The "Eye" of the Opioid Analgesic Addiction Storm – A National Crisis and "REMS" Call to Action: The Essential, Ethical & Obligatory role of Pharmacists and Pharmacy Technicians to Teach, Treat and Educate Patients and Families
USF Health Professions Conferencing Corporation RFA 090618: Opioid Analgesic: Risk Evaluation and Mitigation Strategy (REMS)
Massachusetts Medical Society NEJM Knowledge+ Pain and Addiction Module
Primary Provider Title
Trustees of Boston University Safe and Competent Opioid Prescribing Education for Chronic Pain (SCOPE of Pain): Incorporating ER/LA Opioid Analgesics REMS into Practice
Johns Hopkins University Get SMART 'Mobile'- Safe Means of Administering the Right Therapy (Get SMART Mobile)
Postgraduate Institute for Medicine Safe Means of Administering the Right Therapy - Extended-Release and Long-Acting Opioids (Get SMART ER/LA Opioids)
Pri-Med Institute SAFE Opioid Prescribing; Strategies, Assessment, Fundamentals, and Education
CO*RE Opioid Prescribing Safe Practice, Changing Lives
Global Education Group Extension Grant: Extended-Release and Long-Acting Opioid Analgesics: Risk Evaluation and Mitigation Strategy (REMS)
Primary Provider Title
Trustees of Boston University Safe and Competent Opioid Prescribing Education for Chronic Pain (SCOPE of Pain): Incorporating ER/LA Opioid Analgesics REMS into Practice
Johns Hopkins University Safe Means of Administering the Right Therapy - Extended-Release and Long-Acting Opioids (Get SMART ER/LA Opioids)
Postgraduate Institute for Medicine Safe Means of Administering the Right Therapy - Extended-Release and Long-Acting Opioids (Get SMART ER/LA Opioids)
Pri-Med Institute SAFE Opioid Prescribing; Strategies, Assessment, Fundamentals and Education
CO*RE CO*RE: Opioid Prescribing Safe Practice, Changing Lives
Dannemiller, Inc. REMS Resource: Tools for Safe Opioid Prescribing in Chronic Pain Management
Primary Provider Title
Trustees of Boston University Safe and Competent Opioid Prescribing Education for Chronic Pain (SCOPE of Pain): Incorporating ER/LA Opioid Analgesics REMS into Practice
Johns Hopkins University Safe Means of Administering the Right Therapy - Extended-Release and Long-Acting Opioids (Get SMART ER/LA Opioids)
Florida Medical Association Opioid REMS: Achieving Prescriber Compliance and Patient Satisfaction
Ultimate Medical Academy A Comprehensive Approach to the Safe Management of Extended-Release/Long-Acting Opioids
American Academy of Physical Medicine and Rehabilitation Interactive Educational Arcade on Pain, including Prescriber Education for ER/LA
Postgraduate Institute for Medicine Solutions for Safe ER/LA Opioid Prescribing in a New Era of Health Care Reform. A Multi-disciplinary REMS Initiative for a Changing Health Care Delivery Environment
Postgraduate Institute for Medicine Safe Means of Administering the Right Therapy - Extended-Release and Long-Acting Opioids (Get SMART ER/LA Opioids)
Pri-Med Institute SAFE Opioid Prescribing; Strategies, Assessment, Fundamentals and Education
CO*RE CO*RE 2015: Achieving Safe Use While Improving Patient Care
Primary Provider Title
Trustees of Boston University Safe and Competent Opioid Prescribing Education for Chronic Pain (SCOPE of Pain): Incorporating ER/LA Opioid Analgesics REMS into Practice
Pri-Med Institute, LLC Safe Opioid Prescribing Strategies. Assessment. Fundamentals. Education
University of Washington Collaborative Opioid Prescribing Education (COPE) REMS Training Program
CO*RE CO*RE 2015: Achieving Safe Use While Improving Patient Care
Florida Medical Association Opioid REMS: Achieving Prescriber Compliance and Patient Satisfaction
Postgraduate Institute for Medicine PCE Pain Workshop Series - Safe Means of Administering the Right Therapy - Extended-Release and Long-Acting Opioids (SMART ER/LA OPIOIDS)
Dannemiller, Inc. REMS Resource: Tools for Safe Opioid Prescribing in Chronic Pain Management
Primary Provider Title
University of Washington School of Medicine Collaborative Opioid Prescribing Education (COPE) REMS Training Program
Temple University School of Medicine INSIDE Chronic Pain Management: INspiring System Improvement With Data-Driven Education
Montefiore/Albert Einstein College of Medicine PainEDU REMS Education Program
American Academy of Pain Management The Emerging Solutions in Pain Responsible Opioid Prescribing Initiative
University of Cincinnati College of Medicine A Comprehensive Curriculum to Address "Extended-Release and Long-Acting Opioid Analgesics REMS"
University of Nebraska Medical Center Responsible Opioid Prescribing: A Live and Enduring Educational Program
University of North Texas Health Science Center/Texas College of Osteopathic Medicine Foundation Effective Strategies for Chronic Pain Management: A Risk Evaluation and Mitigation Strategy for ER/LA Opioid Analgesics
Primary Provider Title
Trustees of Boston University SCOPE of Pain: Safe and Competent Opioid Prescribing Education
CO*RE CO*RE REMS Initiative: A Collaborative Solution to the ER/LA Opioid Public Health Crisis
American College of Physicians SAFE Opioid Prescribing: Strategies. Assessment. Fundamentals. Education.
Utah Medical Association Foundation Utah ER/LA Opioid Analgesics Risk Evaluation and Mitigation Strategy (REMS) Educational Programming Project
Association for Hospital Medical Education AHME Collaborative for REMS Education

For further information on the Opioid Analgesic REMS, please refer to the FDA website.

For further inquiries relating to educational grants for the Opioid Analgesic REMS, please refer to the Frequently Asked Questions regarding Continuing Education.